Chemical Name: 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
Biological ActivityCav3.2 (T-type) Ca2+ channel blocker (IC50 = 991 nM). Suppresses neuropathic allodynia in mouse pain models.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice.
Sekiguchi et al.
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