(2R/S)-6-PNG

Key Product Details

Product Description

(2R/S)-6-PNG is a Ca_v3.2 (T-type) Ca²⁺ channel blocker (IC₅₀ = 991 nM). Suppresses neuropathic allodynia in mouse pain models.

Product Specifications for (2R/S)-6-PNG

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (2R/S)-6-PNG

The following data is based on the product molecular weight 340.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.94 mL	14.69 mL	29.38 mL
5 mM	0.59 mL	2.94 mL	5.88 mL
10 mM	0.29 mL	1.47 mL	2.94 mL
50 mM	0.06 mL	0.29 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Sekiguchi Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology 2018 PMID: 29913186

Product Documents for (2R/S)-6-PNG