3',2'-cGAMP sodium salt
Chemical Name: 3',2'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Biological Activity3',2'-cGAMP sodium salt is a second messenger in the antiviral immune response in Drosophila melanogaster and in bacteria. 3',2'-cGAMP is selective for Drosophila stimulator of interferon genes (dSTING); induces expression of STING and STING-related genes. After injection of drosophila C virus dsRNA into Drosophila, 3',2'-cGAMP activates STING-dependent antiviral immunity in vivo, reduces viral RNA load and increases survival. In bacteria 3',2'-cGAMP activates DNA degradation of AsCap5 and LlCap5.
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- This product is sold in units of 359μg, equivalent to 0.5μmol.
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