Chemical Name: 6-(4-Methoxy-3-tricyclo[220.127.116.11,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
Biological Activity Retinoic acid analog that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cell in vitro. Displays comedolytic activity.
Soluble to 25 mM in DMSO
Store at +4°C
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