Alda 1

Key Product Details

Product Description

Alda 1 is an activator of aldehyde dehydrogenase 2 (ALDH2). Increases activity of wild-type ALDH2*1 and variant ALDH2*2 (by ~2-fold and 11-fold respectively). Capable of partly restoring mutant ALDH2*2 activity; protective against cardiac ischemia.

Product Specifications for Alda 1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Alda 1

The following data is based on the product molecular weight 324.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.08 mL	15.42 mL	30.85 mL
5 mM	0.62 mL	3.08 mL	6.17 mL
10 mM	0.31 mL	1.54 mL	3.08 mL
50 mM	0.06 mL	0.31 mL	0.62 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

• Beretta Characterization of the East Asian variant of aldehyde dehydrogenase-2. Bioactivation of nitrogly. and effects of alda-1. J.Biol.Chem. 2010 PMID: 19906643
• Chen An activator of mutant and wildtype aldehyde dehydrogenase reduces ischemic damage to the heart. Science 2008 PMID: 18787169

Product Documents for Alda 1