Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Janelia Fluor 669

Antibody Source

Monoclonal Mouse IgG1 Clone # 409111
View all Aminopeptidase P1/XPNPEP1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Aminopeptidase P1/XPNPEP1
Met1-Gln622
Accession # Q9NQW7

Specificity

Detects human Aminopeptidase P1/XPNPEP1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) XPNPEP1, rmXPNPEP2, or recombinant human XPNPEP2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Aminopeptidase P1/XPNPEP1 Antibody (409111) [Janelia Fluor® 669]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Aminopeptidase P1/XPNPEP1

XPNPEP1 is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. As a result of its specificity toward proline, it has been suggested that XPNPEP1 is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of XPNPEP1 results in excretion of large amounts of imino-oligopeptides in urine.

Alternate Names

APP1, SAMP, XPNPEP1

Gene Symbol

XPNPEP1

Additional Aminopeptidase P1/XPNPEP1 Products

Product Documents for Aminopeptidase P1/XPNPEP1 Antibody (409111) [Janelia Fluor® 669]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Aminopeptidase P1/XPNPEP1 Antibody (409111) [Janelia Fluor® 669]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Metalloproteases and Regulators

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