Amiodarone hydrochloride

Catalog # Availability Size / Price Qty
4095/50
Ion Channel Modulators Small Molecule
1 Image
Description: Broad spectrum ion channel blocker; antiarrhythmic

Chemical Name: 2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Broad-spectrum ion channel blocker; blocks late INa, ICa, IKr and IKs and increases QT. Displays class III antiarrhythmic properties. Also exhibits fungicidal activity; elicits Ca2+ influx in Saccharomyces cerevisiae and causes mitochondrial fragmentation and cell death. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways. Selectively toxic to NSCs in hESC-derived cell populations.

Technical Data

M.Wt:
681.77
Formula:
C25H29I2NO3.HCl
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
19774-82-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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⚠ WARNING: This product can expose you to chemicals including Amiodarone hydrochloride, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citation for Amiodarone hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Amiodarone hydrochloride include:

1 Citation: Showing 1 - 1

  1. Amiodarone inhibits apamin-sensitive potassium currents.
    Authors: Turker Et al.
    PLoS One  2013;8:e70450

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