Anagrelide hydrochloride

Tocris Bioscience | Catalog # 2432

Potent PDE3 inhibitor
Tocris Bioscience
Discontinued Product
2432 has been discontinued. View all Phosphodiesterase Inhibitors products.

Key Product Details

Description

Potent PDE3 inhibitor

Alternative Names

BL 4162A
View all Phosphodiesterase Inhibitors »

Product Description

Anagrelide hydrochloride is a potent type III phosphodiesterase (PDE3) inhibitor (IC50 = 36 nM). Inhibits platelet aggregation and produces potent thrombocytopenic effects via inhibition of megakaryocyte maturation.

Product Specifications for Anagrelide hydrochloride

Molecular Weight

292.55

Formula

C10H7Cl2N3O.HCl

Storage

Desiccate at +4°C

Purity

≥99% (HPLC)

Chemical Name

6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride

CAS Number

58579-51-4

PubChem ID

42786

InChI Key

TVWRQCIPWUCNMI-UHFFFAOYSA-N

SMILES

ClC1=C(CN(C3)C(N2)=NC3=O)C2=CC=C1Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.93 10

Preparing Stock Solutions for Anagrelide hydrochloride

The following data is based on the product molecular weight 292.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.18 mL 170.91 mL 341.82 mL
0.5 mM 6.84 mL 34.18 mL 68.36 mL
1 mM 3.42 mL 17.09 mL 34.18 mL
5 mM 0.68 mL 3.42 mL 6.84 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Anagrelide hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Anagrelide hydrochloride

For research use only

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