Chemical Name: 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride
Biological ActivityAnagrelide hydrochloride is a potent type III phosphodiesterase (PDE3) inhibitor (IC50 = 36 nM). Inhibits platelet aggregation and produces potent thrombocytopenic effects via inhibition of megakaryocyte maturation.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Anagrelide: a potent and selective inhibitor of platelet cyclic AMP phosphodiesterase enzyme activity.
Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans.
Mazur et al.
Comparison of the biological activities of anagr. and its major metabolites in haematopoietic cell cultures.
Wang et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Anagrelide hydrochloride
There are currently no reviews for this product. Be the first to review Anagrelide hydrochloride and earn rewards!
Have you used Anagrelide hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image