Auranofin

Catalog # Availability Size / Price Qty
4600/10
4600/50
Other Reductase Inhibitors Small Molecule
1 Image
Description: Thioredoxin reductase inhibitor; induces MPT

Chemical Name: 1-Thio-β-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate

Product Details
Citations (1)
Reviews

Biological Activity

Inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Thought to induce the mitochondrial permeability transition via inhibition of mitochondrial TrxR. Also exhibits anti-inflammatory and immunosuppressive activities; inhibits 5-lipoxygenase at high concentrations and stimulates LTA hydrolase at low concentrations.

Technical Data

M.Wt:
678.48
Formula:
C20H34AuO9PS
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage:
Store at RT
CAS No:
34031-32-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Auranofin, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citation for Auranofin

The citations listed below are publications that use Tocris products. Selected citations for Auranofin include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Auranofin

There are currently no reviews for this product. Be the first to review Auranofin and earn rewards!

Have you used Auranofin?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.