Chemical Name: (4R)-rel-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester hydrochloride
Biological ActivityOrally active antihypertensive agent which displays a wide range of activities in vitro and in vivo. Inhibits L-, N- and T-type Ca2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacological, pharmacokinetic, and clinical properties of benidipine hydrochloride, a novel long-acting calcium channel blocker.
Yao et al.
The L-, N-, T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family.
Kosaka et al.
Citation for Benidipine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Benidipine hydrochloride include:
1 Citation: Showing 1 - 1
Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling.
Authors: Bhandage Et al.
Front Cell Infect Microbiol 2019;9:73
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