Orally active antihypertensive agent which displays a wide range of activities in vitro
and in vivo
. Inhibits L-, N- and T-type Ca2+
channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
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All Tocris products are intended for laboratory research use only.
Pharmacological, pharmacokinetic, and clinical properties of benidipine hydrochloride, a novel long-acting calcium channel blocker.
Yao et al.
The L-, N-, T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family.
Kosaka et al.