Catalog # Availability Size / Price Qty
BHQ | CAS No. 88-58-4 | Ca2+-ATPase Inhibitors
1 Image
Description: Inhibitor of SERCA ATPase

Chemical Name: 1,4-Dihydroxy-2,5-di-tert-butylbenzene

Product Details
Citations (3)
Reviews (1)

Biological Activity

A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.

Technical Data

Soluble to 100 mM in DMSO
Store the unopened product at room temperature. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Citations for BHQ


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for BHQ

Average Rating: 4 (Based on 1 Review)

5 Star
4 Star
3 Star
2 Star
1 Star

Have you used BHQ?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:

BHQ depletes ER Ca2+ store in HEK cells leading to STIM1-Orai1 clustering for store-operated Ca2+ entry.
By Niroj Shrestha on 10/27/2018
Species: Human

ER resident protein, STIM1 and PM resident Orai1 channel were expressed with YFP and CFP fluorescent tags respectively in HEK293 cells and imaged using TIRF microscopy. Basal STIM1 and Orai1 (left) co-clusters to form punctae at PM-ER junctions upon ER store depletion (right) by BHQ (30 µM), leading to store-operated Ca2+ entry through Orai1.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.