BHQ

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Disturbance of Ca2+ homeostasis converts pro-Met into non-canonical tyrosine kinase p190MetNC in response to endoplasmic reticulum stress in MHCC97 cells.
   Dai R, Li J, Fu J, Chen Y, Yu L, Zhao X, Qian Y, Zhang H, Chen H, Ren Y, Su B, Luo T, Zhu J, Wang H
   J. Biol. Chem., 2012;287(18):14586-97.
2. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
3. Effects of three sarcoplasmic/endoplasmic Ca⁺⁺ pump inhibitors on release channels and intracellular stores.
   Dettbarn and Palade
   J.Pharmacol.Exp.Ther., 1999;285:739
4. Blockade of the inward rectifier potassium current by the Ca²⁺-ATPase inhibitor 2',5'-di(tert-butyl)-1,4-benzohydroquinone (BHQ).
   Hassessian et al.
   Br.J.Pharmacol., 1994;112:1118
5. 2,5-Di-t-butyl-1,4 benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta.
   Fusi et al.
   Eur.J.Pharmacol., 1999;366:181
6. Mechanism of rise and decay of 2,5-di-tert-butylhydroquinone-induced Ca²⁺ signals in Madin Darby canine kidney cells.
   Jan et al.
   Eur.J.Pharmacol., 1999;365:111

Product Datasheets