BHQ

Tocris Bioscience | Catalog # 1236

Inhibitor of SERCA ATPase
Tocris Bioscience
Discontinued Product
1236 has been discontinued. View all Ca2+-ATPase Inhibitors products.

Key Product Details

Description

Inhibitor of SERCA ATPase
View all Ca2+-ATPase Inhibitors »

Product Description

BHQ is a selective inhibitor of endoplasmic reticulum Ca2+-ATPase.

Product Specifications for BHQ

Molecular Weight

222.33

Formula

C14H22O2

Storage

Store at RT

Chemical Name

1,4-Dihydroxy-2,5-di-tert-butylbenzene

CAS Number

88-58-4

PubChem ID

2374

InChI Key

JZODKRWQWUWGCD-UHFFFAOYSA-N

SMILES

CC(C)(C)C1=CC(O)=C(C=C1O)C(C)(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100

Preparing Stock Solutions for BHQ

The following data is based on the product molecular weight 222.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.50 mL 22.49 mL 44.98 mL
5 mM 0.90 mL 4.50 mL 9.00 mL
10 mM 0.45 mL 2.25 mL 4.50 mL
50 mM 0.09 mL 0.45 mL 0.90 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for BHQ

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BHQ

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for BHQ (1)

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Customer Images

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  • BHQ depletes ER Ca2+ store in HEK cells leading to STIM1-Orai1 clustering for store-operated Ca2+ entry.
    Name: Niroj Shrestha
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HEK293
    Verified Customer | Posted 10/27/2018
    ER resident protein, STIM1 and PM resident Orai1 channel were expressed with YFP and CFP fluorescent tags respectively in HEK293 cells and imaged using TIRF microscopy. Basal STIM1 and Orai1 (left) co-clusters to form punctae at PM-ER junctions upon ER store depletion (right) by BHQ (30 µM), leading to store-operated Ca2+ entry through Orai1.
    BHQ 1236

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