BIBN 4096

Catalog # Availability Size / Price Qty
4561/10
BIBN 4096 | CAS No. 204697-65-4 | Calcitonin and Related Receptor Antagonists
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Description: Potent and selective CGRP antagonist
Alternative Names: Olcegepant

Chemical Name: 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine

Purity: ≥95%

Product Details
Citations (4)
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Biological Activity

BIBN 4096 is a potent and selective CGRP receptor antagonist (IC50 values are 0.03 and 6.4 nM for human and rat CGRP receptors respectively). Displays high affinity for human CGRP receptors (Ki = 14.4 pM); exhibits no significant affinity for 75 other receptors.

Technical Data

M.Wt:
869.65
Formula:
C38H47Br2N9O5
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in 2eq.HCl
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
204697-65-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for BIBN 4096

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4 Citations: Showing 1 - 4

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