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4 results for "Calcitonin and Related Receptor Antagonists" in Products
Calcitonin and Related Receptor Antagonists
Calcitonin and related receptors are a family of G-protein-coupled receptors that comprises eight subtypes; CT, AMY1, AMY2, AMY3, CALCR, CGRP, AM1 and AM2. The receptors have a wide biological distribution; high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid.
The main function of CT receptors is to inhibit bone reabsorption and enhance calcium excretion by the kidneys. AMY receptors are ...
Potent and selective CGRP antagonist
| Alternate Names: | Olcegepant |
| Chemical Name: | 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine |
| Purity: | ≥95% |
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CGRP antagonist
| Alternate Names: | Calcitonin Gene-Related Peptide 8-37 (rat) |
| Purity: | ≥95% |
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CGRP antagonist
| Alternate Names: | Calcitonin Gene-Related Peptide 8-37 (human) |
| Purity: | ≥95% |
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Potent and selective amylin antagonist
| Purity: | ≥95% |
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