Bicalutamide

Catalog # Availability Size / Price Qty
3389/10
3389/50
Androgen Receptor Antagonists Small Molecule
1 Image
Description: Non-steroidal androgen receptor antagonist
Alternative Names: Casodex, ICI 176,334

Chemical Name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide

Purity: ≥99%

Product Details
Citations (4)
Supplemental Products
Reviews (1)

Biological Activity

Orally active non-steroidal androgen receptor antagonist (IC50 = 190 nM). Displays peripheral selectivity and does not effect serum levels of LH and testosterone. Exhibits potent anticancer activity in vivo.

Technical Data

M.Wt:
430.37
Formula:
C18H14F4N2O4S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
90357-06-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes only under agreement from AstraZeneca

Product Datasheets

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Citations for Bicalutamide

The citations listed below are publications that use Tocris products. Selected citations for Bicalutamide include:

4 Citations: Showing 1 - 4

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In vitro culture with c4-2 cells to induce AR reduction
By Anonymous on 11/03/2019
Species: Human

in vitro culture with c4-2 cells to induce AR reduction

PMID: 26945682

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