BzF
1 Image
Description: Photoreactive unnatural amino acid; photo-crosslinker
Chemical Name: 4-Benzoyl-L-phenylalanine
Purity: ≥98%
Biological Activity
BzF is a photoreactive unnatural amino acid. Acts as photo cross-linking probe when incorporated into proteins, including ion channels, transporters and GPCRs. When exposed to UV light it forms a covalent cross-link with a C-H bond-containing group, enabling selective and potent UV-driven photoinactivation of protein function. Has been used to study protein-protein and protein-ligand interactions.Technical Data
M.Wt:
269.3
Formula:
C16H15NO3
Solubility:
Soluble to 50 mM in 80% acetic acid
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
104504-45-2
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis.
Ye et al.
J.Biol.Chem., 2008;283:1525 -
Probing ion channel structure and function using light-sensitive amino acids.
Klippenstein et al.
Trends Biochem.Sci., 2018;43:436 -
Photoinactivation of glutamate receptors by genetically encoded unnatural amino acids.
Klippenstein et al.
J.Neurosci., 2014;34:980
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for BzF
There are currently no reviews for this product. Be the first to review BzF and earn rewards!
Have you used BzF?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris Bioscience is the leading supplier of novel and exclusive
tools for
life science research with over 30 years' experience in the
industry.
Tocris is a Bio-Techne brand.
