BzF

Key Product Details

Product Description

BzF is a photoreactive unnatural amino acid. Acts as photo cross-linking probe when incorporated into proteins, including ion channels, transporters and GPCRs. When exposed to UV light it forms a covalent cross-link with a C-H bond-containing group, enabling selective and potent UV-driven photoinactivation of protein function. Has been used to study protein-protein and protein-ligand interactions.

Product Specifications for BzF

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BzF

The following data is based on the product molecular weight 269.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	7.43 mL	37.13 mL	74.27 mL
2.5 mM	1.49 mL	7.43 mL	14.85 mL
5 mM	0.74 mL	3.71 mL	7.43 mL
25 mM	0.15 mL	0.74 mL	1.49 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Klippenstein Probing ion channel structure and function using light-sensitive amino acids. Trends Biochem.Sci. 2018 PMID: 29650383
• Klippenstein Photoinactivation of glutamate receptors by genetically encoded unnatural amino acids. J.Neurosci. 2014 PMID: 24431456
• Ye Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J.Biol.Chem. 2008 PMID: 17993461

Product Documents for BzF