Canrenone
Discontinued Product
Chemical Name: (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid γ-lactone
Purity: ≥98%
Biological Activity
Canrenone is a mineralocorticoid receptor antagonist. Active metabolite of spironolactone (Cat. No. 2968).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRgamma activation.
Leung W, Vong Q, Lin W, Janke L, Chen T, Leung W
J Exp Med, 2013;210(12):2675-92. -
Mineralocorticoid receptor antagonists: the evolution of utility and pharmacology.
Delyani et al.
Kidney Int., 2000;57:1408
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Citation for Canrenone
The citations listed below are publications that use Tocris products. Selected citations for Canrenone include:
1 Citation: Showing 1 - 1
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Spironolactone blocks Epstein-Barr virus production by inhibiting EBV SM protein function.
Authors: Verma Et al.
Proc Natl Acad Sci U S A 2016;113:3609
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