2 results for "Mineralocorticoid Receptor Antagonists" in Products

Mineralocorticoid Receptor Antagonists

Mineralocorticoid Receptor (MR) is a member of the nuclear hormone receptor family. Upon binding of ligand (aldosterone or corticosterone) mineralocorticoid receptors translocate to the nucleus and can form either homo or heterodimers. MR dimers bind to the mineralocorticoid response element (AGAACANNNTGTTCT) to regulate gene transcription. There a...

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Selective mineralocorticoid receptor antagonist

Alternate Names: Inspra,Epoxymexrenone
Chemical Name: (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid γ-lactone methyl ester
Purity: ≥98%
Selective mineralocorticoid receptor antagonist
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Mineralocorticoid receptor antagonist

Alternate Names: SC 9420,Aldactone
Chemical Name: (7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone
Purity: ≥98%
Mineralocorticoid receptor antagonist
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