CDPPB

Catalog # Availability Size / Price Qty
3235/10
3235/50
CDPPB | CAS No. 781652-57-1 | Group I mGluR Modulators
1 Image
Description: Positive allosteric modulator of mGlu5 receptors

Chemical Name: 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide

Purity: ≥98%

Product Details
Citations (5)
Supplemental Products
Reviews

Biological Activity

Brain penetrant, selective positive allosteric modulator at the mGlu5 receptor (EC50 values are 10 and 20 nM for human and rat receptors respectively). Antipsychotic; reverses amphetamine-induced locomotor activity and amphetamine-induced deficits in prepulse inhibition in rats.

Technical Data

M.Wt:
364.4
Formula:
C23H16N4O
Solubility:
Soluble to 75 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
781652-57-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Manufactured and sold under license from Merck & Co., Inc. for use solely for preclinical research purposes (ie: not for administration to or other use in humans)

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for CDPPB

The citations listed below are publications that use Tocris products. Selected citations for CDPPB include:

5 Citations: Showing 1 - 5

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for CDPPB

There are currently no reviews for this product. Be the first to review CDPPB and earn rewards!

Have you used CDPPB?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.