Biological Activity Potassium channel blocker; inhibits the pacemaker current (If) and the hyperpolarization-activated cationic current (Ih). Prevents activation of caspase-3 and neuronal apoptosis in serum- and potassium-deprived cerebellar granule neurons by inactivating GSK-3β.
Soluble to 100 mM in water
Desiccate at RT
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All Tocris products are intended for laboratory research use only.
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