CGS 15943

  ( 5 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:1699
Chemical Name:9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Potent adenosine receptor antagonist (Ki values are 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively). Orally active in vivo.
Technical Data
  • M.Wt:
    285.69
  • Formula:
    C13H8ClN5O
  • Solubility:
    Soluble to 5 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    104615-18-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for CGS 15943 include:

5 Citations: Showing 1 - 5
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  1. Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling
    Authors: Avanzato Et al.
    Scientific Reports  2016;6:32602
  2. Application of BRET to monitor ligand binding to GPCRs.
    Authors: Stoddart Et al.
    Nat Methods  2015;12:661
  3. Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.
    Authors: Diógenes Et al.
    Cereb Cortex  2014;24:67
  4. Adenosine release during seizures attenuates GABAA receptor-mediated depolarization.
    Authors: Ilie Et al.
    J Neurosci  2012;32:5321
  5. Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes.
    Authors: Sivaramakrishnan Et al.
    J Cell Sci  2012;125:4567

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VersaClone cDNA Plasmids
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Mouse Adenosine A1 R (NP_000665) VersaClone cDNA

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Average Rating: 5 (Based on 1 review)

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  Mouse Ariel Vitenzon 01/05/2018
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Summary

Species Mouse

Other Experimental Details

Other Experimental Details Drug was dissolved using saline + 0.3% tween 80. (Vortexed for 1 minute and sonicated for 5 min) X3 times.

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