Mouse Adenosine A2aR (NP_033760) VersaClone cDNA Summary
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Background: Adenosine A2aR
Adenosine A2A Receptor (ADORA2A, Adenosine A2aR) is one of several receptor subtypes for adenosine. The activity ofAdenosine A2aR, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. Adenosine A2aR is abundant in basal ganglia, vasculature and platelets and is a major target of caffeine. Variability in the acute blood pressure response to coffee may be partly explained by genetic polymorphisms of the adenosine A2A receptors, including Adenosine A2aR, and alpha(2)-adrenergic receptors.
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