CHC

  ( 1 citations )    
Product Datasheet
Catalog Number:5029
Chemical Name:2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid
Product Details
Citations (1)
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Biological Activity
Monocarboxylic acid transport (MCT) inhibitor. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo; decreases glycolytic metabolism, migration, and invasion in U251 cells. Enhances the effect of antitumor agent temozolomide (Cat No. 2706). Blocks lactate efflux from glioma cells and sensitizes cells to irradiation.
Technical Data
  • M.Wt:
    189.17
  • Formula:
    C10H7NO3
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    28166-41-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CHC include:

1 Citations: Showing 1 - 1

  1. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
    Authors: Jang Et al.
    Nat Med  2016;22:421

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