Chemical Name: 1-(2-Chloro-α,α-diphenylbenzyl)imidazole
Biological Activity Imidazole antimycotic and cytochrome P450 inhibitor. Inhibits Ca2+-activated K+ current (IC50 = 3 μM) and L-type Ca2+ current; increases the firing rate of action potentials. Exhibits antiproliferative activity in vitro and in vivo. Also an inverse agonist of the human constitutive androstane receptor (hCAR).
Soluble to 75 mM in DMSO and to 100 mM in ethanol
Store at RT
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