Catalog Number: 2951
Alternate Names: Des-acyl ghrelin (rat)
Biological Activity
Non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release.
Technical Data
  • M.Wt:
    3188.63
  • Formula:
    C139H231N45O41
  • Sequence:
    GSSFLSPEHQKAQQRKESKKPPAKLQPR
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    307950-60-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin.
    Bedendi et al.
    Eur.J.Pharmacol., 2003;476:87
  2. Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines.
    Cassoni et al.
    Eur.J.Endocrinol., 2004;150:173
  3. Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor
    Thompson et al.
    Endocrinology, 2004;145:234
Citations:

The citations listed below are publications that use Tocris products. Selected citations for [Des-octanoyl]-Ghrelin (rat) include:

2 Citations: Showing 1 - 2
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  1. Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition.
    Authors: Engel Et al.
    Psychopharmacology (Berl) 2015;232:4285
  2. Intrarenal ghrelin infusion stimulates distal nephron-dependent sodium reabsorption in normal rats.
    Authors: Kemp Et al.
    Br J Pharmacol 2011;57:633

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