Biological Activity[Des-octanoyl]-Ghrelin (rat) is a non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin.
Bedendi et al.
Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines.
Cassoni et al.
Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a GH secretagogue receptor
Thompson et al.
Citations for [Des-octanoyl]-Ghrelin (rat)
The citations listed below are publications that use Tocris products. Selected citations for [Des-octanoyl]-Ghrelin (rat) include:
2 Citations: Showing 1 - 2
Blockade of GH secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition.
Authors: Engel Et al.
Psychopharmacology (Berl) 2015;232:4285
Intrarenal ghrelin infusion stimulates distal nephron-dependent sodium reabsorption in normal rats.
Authors: Kemp Et al.
Br J Pharmacol 2011;57:633
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