Cell-permeable version of dynamin inhibitory peptide
(Cat. No. 1774), an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons.
Kittler et al.
The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence.
Grabs et al.
Glycine binding primes NMDA receptor internalization.
Nong et al.
The citations listed below are publications that use Tocris products. Selected citations for Dynamin inhibitory peptide, myristoylated include:
Showing Results 1 - 4 of 4