Edelfosine

Catalog # Availability Size / Price Qty
3022/10
Cat.No. 3022 - Edelfosine | C27H58NO6P | CAS No. 77286-66-9
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Description: Selective PI-PLC inhibitor, also PAF receptor agonist
Alternative Names: ET-18-OCH3

Chemical Name: (7R)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium-4-oxide

Product Details
Citations (7)
Reviews

Biological Activity

Synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC50= 9.6 μM in fibroblasts and adenocarcinoma cells). Also acts as an agonist at platelet-activating factor (PAF) receptors. Antitumor lipid; selectively induces apoptosis in tumor cells, sparing normal cells.

Technical Data

M.Wt:
523.73
Formula:
C27H58NO6P
Solubility:
Soluble to 5 mM in water with gentle warming and to 100 mM in ethanol
Storage:
Store at -20°C
CAS No:
77286-66-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citations for Edelfosine

The citations listed below are publications that use Tocris products. Selected citations for Edelfosine include:

7 Citations: Showing 1 - 7

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