Selective mineralocorticoid (aldosterone) receptor antagonist (IC50
= 360 nM). Displays > 27-fold selectivity over androgen, progesterone and estrogen receptors (IC50
> 10 μ
M). Orally active antihypertensive in vivo
Soluble to 10 mM in DMSO
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro.
De Gasparo et al.
Recent studies with eplerenone, a novel selective aldosterone receptor antagonist.
McMahon and Cunningham
The citations listed below are publications that use Tocris products. Selected citations for Eplerenone include:
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