Glucagon-like peptide 1 (7-36) amide (human, rat)

   
Product Datasheet
Catalog Number:2082
Alternate Names:GLP-1 (7-36) amide
Chemical Name:
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Biological Activity
Potent glucose-dependent insulinotropic peptide produced by post-translational processing of proglucagon in intestinal L-cells. Displays high affinity for GLP-1 receptors expressed in rat insulinoma-derived RINm5F cells (Kd = 204 pM). Stimulates insulin gene transcription and secretion in pancreatic β-cells. Displays antiapoptotic effects in hippocampal neurons and reduces food intake in fasted rats following central administration.
Technical Data
  • M.Wt:
    3297.67
  • Formula:
    C149H226N40O45
  • Sequence:
    HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR

    (Modifications: Arg-30 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    107444-51-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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