Glucagon-like peptide 1 (7-36) amide (human, rat)

Tocris Bioscience | Catalog # 2082

Potent insulinotropic peptide
Tocris Bioscience

Key Product Details

Description

Potent insulinotropic peptide

Alternative Names

GLP-1 (7-36) amide
View all Glucagon-Like Peptide 1 Receptor Agonists »

Product Description

Glucagon-like peptide 1 (7-36) amide (human, rat) is a potent glucose-dependent insulinotropic peptide produced by post-translational processing of proglucagon in intestinal L-cells. Displays high affinity for GLP-1 receptors expressed in rat insulinoma-derived RINm5F cells (Kd = 204 pM). Stimulates insulin gene transcription and secretion in pancreatic β-cells. Displays antiapoptotic effects in hippocampal neurons and reduces food intake in fasted rats following central administration.

Product Specifications for Glucagon-like peptide 1 (7-36) amide (human, rat)

Molecular Weight

3297.67

Formula

C149H226N40O45

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

107444-51-9

PubChem ID

16133831

InChI Key

DTHNMHAUYICORS-KTKZVXAJSA-N

SMILES

[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for Glucagon-like peptide 1 (7-36) amide (human, rat)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Glucagon-like peptide 1 (7-36) amide (human, rat)

For research use only

Citations for Glucagon-like peptide 1 (7-36) amide (human, rat)

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