7 results for "Glucagon-Like Peptide 1 Receptor Agonists" in Products
Glucagon-Like Peptide 1 Receptor Agonists
Glucagon-like peptide 1 (GLP-1) receptors are members of the glucagon receptor family that also includes glucagon, GLP-2, secretin, GHRH and GIP receptors. GLP-1 receptors are found both centrally (hypothalamus and brainstem) and peripherally (pancreatic islet cells, stomach and heart).
GLP-1 receptors mediate the effects of the incretin axis; the functional connection between the intestine and the islets of Langerhans in the pancreas. Activation stimulates insulin release from the islet β-cells in a glucose-dependent manner and suppresses glucagon secretion from islet α-cells. In addition, GLP-1 receptors delay gastric emptying and regulate appetite. The human GLP-1 receptor gene is localized on chromosome 6p21.
Potent GLP-1 receptor agonist
| Alternate Names: | Exenatide,AC 2993 |
| Purity: | ≥95% |
Endogenous bioactive GLP-1 receptor ligand
| Purity: | ≥95% |
Highly potent, long-acting GLP-1 receptor agonist
| Alternate Names: | NN2211 |
| Purity: | ≥95% |
Potent insulinotropic peptide
| Alternate Names: | GLP-1 (7-36) amide |
| Purity: | ≥95% |
Endogenous pancreatic peptide
| Alternate Names: | GLP-1 (1-37) amide |
| Purity: | ≥95% |
Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator
| Chemical Name: | (R)-2-(2-(1-((R)-1-(2,6-Dichloro-3-cyclopropylphenyl)ethyl)-1H-imidazo[4,5-c]pyridin-6-yl)phenyl)propanoic acid |
| Purity: | ≥98% |
GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist
| Chemical Name: | 6,7-Dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-2-quinoxalinamine |
| Purity: | ≥98% |
