GR/NR3C1 Antibody (S02-5A3)

Novus Biologicals | Catalog # NBP3-19823

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-5A3 expressed in HEK293
View all GR/NR3C1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein of human GR/NR3C1 (Uniprot # P04150)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

94 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GR/NR3C1 Antibody (S02-5A3)

Western Blot: GR/NR3C1 Antibody (S02-5A3) [NBP3-19823]

Western Blot: GR/NR3C1 Antibody (S02-5A3) [NBP3-19823]

Western Blot: GR/NR3C1 Antibody (S02-5A3) [NBP3-19823] - Western blot detection of GR/NR3C1 in CHO-K1 (Lane 1), C6 (Lane 2), Rat Brain (Lane 3), Ramos (Lane 4) cell lysates using NBP3-19823 (1:1000 diluted). Predicted band size: 86kDa. Observed band size: 86kDa.

Applications for GR/NR3C1 Antibody (S02-5A3)

Application
Recommended Usage

Western Blot

1/2000-1/10000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GR/NR3C1

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor. The corresponding gene for the glucocorticoid receptor is NR3C1.

Long Name

Glucocorticoid Receptor

Alternate Names

NR3C1

Gene Symbol

NR3C1

Additional GR/NR3C1 Products

Product Documents for GR/NR3C1 Antibody (S02-5A3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for GR/NR3C1 Antibody (S02-5A3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

TGF-beta Signaling Pathways TGF-beta Signaling Pathway Thumbnail