Gue 1654

Tocris Bioscience | Catalog # 4742

Selective inhibitor of OXE-R Gβ/γ signaling
Tocris Bioscience
Discontinued Product
4742 has been discontinued. View all G Protein (Heterotrimeric) Inhibitors products.

Key Product Details

Description

Selective inhibitor of OXE-R Gβ/γ signaling
View all G Protein (Heterotrimeric) Inhibitors »

Product Description

Gue 1654 is an oxoeicosanoid receptor 1 (OXE-R) modulator. Selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R. Inhibits Gβγ-mediated opening of GIRK1/2 channels in HEK293 cells.

Product Specifications for Gue 1654

Molecular Weight

447.60

Formula

C23H17N3OS3

Storage

Store at +4°C

Purity

≥97% (HPLC)

Chemical Name

N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide

CAS Number

397290-30-1

PubChem ID

5066134

InChI Key

UFOBDFMYJABXGK-UHFFFAOYSA-N

SMILES

O=C(C(C5=CC=CC=C5)C4=CC=CC=C4)NC(S3)=NC1=C3C(SC(SC)=N2)=C2C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 22.38 50

Preparing Stock Solutions for Gue 1654

The following data is based on the product molecular weight 447.60.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.47 mL 22.34 mL 44.68 mL
2.5 mM 0.89 mL 4.47 mL 8.94 mL
5 mM 0.45 mL 2.23 mL 4.47 mL
25 mM 0.09 mL 0.45 mL 0.89 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Gue 1654

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gue 1654

For research use only

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