Gue 1654

Catalog # Availability Size / Price Qty
4742/10
4742/50
Cat.No. 4742 - Gue 1654 | C23H17N3OS3 | CAS No. 397290-30-1
1 Image
Description: Selective inhibitor of OXE-R Gβγ signaling

Chemical Name: N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide

Purity: ≥97%

Product Details
Citations (1)
Supplemental Products
Reviews

Biological Activity

Oxoeicosanoid receptor 1 (OXE-R) modulator. Selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R. Inhibits Gβγ-mediated opening of GIRK1/2 channels in HEK293 cells.

Technical Data

M.Wt:
447.6
Formula:
C23H17N3OS3
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥97%
Storage:
Store at +4°C
CAS No:
397290-30-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer
    Blättermann et al.
    Nat.Chem.Biol., 2012;8:631

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for Gue 1654

The citations listed below are publications that use Tocris products. Selected citations for Gue 1654 include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for Gue 1654

There are currently no reviews for this product. Be the first to review Gue 1654 and earn rewards!

Have you used Gue 1654?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.