HTRA2/Omi Antibody (4H8C4)

Novus Biologicals | Catalog # NBP3-16294

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4H8C4 expressed in HEK293
View all HTRA2/Omi Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HTRA2/Omi (O43464). GTRSRAWLAVALGAGGAVLLLLWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVV

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HTRA2/Omi Antibody (4H8C4)

Western Blot: HTRA2/Omi Antibody (4H8C4) [NBP3-16294]

Western Blot: HTRA2/Omi Antibody (4H8C4) [NBP3-16294]

Western Blot: HTRA2/Omi Antibody (4H8C4) [NBP3-16294] - Western blot analysis of extracts of various cell lines, using HTRA2/Omi Rabbit mAb (NBP3-16294) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for HTRA2/Omi Antibody (4H8C4)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HTRA2/Omi

HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).

Long Name

High Temperature Requirement Protein-2

Alternate Names

Omi, PRSS25

Gene Symbol

HTRA2

Additional HTRA2/Omi Products

Product Documents for HTRA2/Omi Antibody (4H8C4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for HTRA2/Omi Antibody (4H8C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

Apoptosis Signaling Pathway Apoptosis Signaling Pathway Thumbnail