Human Active MMP-1 Fluorokine E Kit

R&D Systems | Catalog # F1M00

Contains Mercury, Dispose According to Local, State or Federal Laws. Contains p-Aminophenylmercuric Acetate (APMA), a mercury compound. Review Safety Data Sheet (SDS) before use for safety instructions.
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Key Product Details

Species

Human

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: MMP-1

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

Long Name

Matrix Metalloproteinase 1

Alternate Names

MMP1

Entrez Gene IDs

4312 (Human); 83995 (Mouse)

Gene Symbol

MMP1

Additional MMP-1 Products

Product Documents for Human Active MMP-1 Fluorokine E Kit

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Active MMP-1 Fluorokine E Kit

For research use only

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov.

Citations for Human Active MMP-1 Fluorokine E Kit

Customer Reviews for Human Active MMP-1 Fluorokine E Kit (3)

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  • MMP1 activity assay
    Name: Anonymous
    Sample Tested: fibroblasts
    Species: Human
    Verified Customer | Posted 07/30/2024
    MMP1 Fluorokine E Kit standard curve
    We used it to measure inflammation induced-MMP1 activity in human dermal fibroblasts in vitro. Cells were seeded, treated with differnt cytokines and supernatant collected for quantification with the MMP1 kit.
    Human Active MMP-1 Fluorokine E Kit F1M00
  • Human Active MMP-1 Fluorokine E Kit
    Name: Leslie Priddy
    Verified Customer | Posted 04/04/2018
  • Human Active MMP-1 Fluorokine E Kit
    Name: Boubacar Barry
    Verified Customer | Posted 08/11/2017

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