CEACAM-8 (Carcinoembryonic Antigen-related Cell Adhesion Molecule 8) also known as CD66b, CD67 and NCA-95, is a 90 kDa member of the CEACAM subfamily of the CEA family of proteins. It is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. Mature human CEACAM-8 is a 287 amino acid GPI-linked glycoprotein. It contains one V-type and two C2-type Ig-like domains. No definitive rodent CEACAM-8 has been reported.
Human CEACAM‑8/CD66b PE‑conjugated Antibody
R&D Systems | Catalog # FAB4246P
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Gln35-His141
Accession # P31997
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human CEACAM‑8/CD66b PE‑conjugated Antibody
Detection of CEACAM‑8/CD66b in Human Blood Granulocytes by Flow Cytometry.
Human peripheral blood granulocytes were stained with Mouse Anti-Human CEACAM-8/CD66b PE-conjugated Monoclonal Antibody (Catalog # FAB4246P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.Detection of CEACAM‑8/CD66b in HEK293 Human Cell Line Transfected with Human CEACAM-8/CD66b and eGFP by Flow Cytometry.
HEK293 human embryonic kidney cell line transfected with either (A) human CEACAM-8/CD66b or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human CEACAM-8/CD66b PE-conjugated Monoclonal Antibody (Catalog # FAB4246P). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.Applications for Human CEACAM‑8/CD66b PE‑conjugated Antibody
Flow Cytometry
Sample: Human peripheral blood granulocytes and HEK293 human embryonic kidney cell line transfected with human CEACAM-8/CD66b and eGFP
Reviewed Applications
Read 1 review rated 5 using FAB4246P in the following applications:
Spectra Viewer
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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra ViewerFlow Cytometry Panel Builder
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Advanced Features
- Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
- Spillover Popups - Visualize the spectra of individual fluorochromes
- Antigen Density Selector - Match fluorochrome brightness with antigen density
Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CEACAM-8/CD66b
Long Name
Alternate Names
Gene Symbol
UniProt
Additional CEACAM-8/CD66b Products
Product Documents for Human CEACAM‑8/CD66b PE‑conjugated Antibody
Certificate of Analysis
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Product Specific Notices for Human CEACAM‑8/CD66b PE‑conjugated Antibody
For research use only
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Customer Reviews for Human CEACAM‑8/CD66b PE‑conjugated Antibody (1)
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Application: Flow CytometrySample Tested: Blood mononuclear cells (PBMCs)Species: HumanVerified Customer | Posted 12/16/2017
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