Human GCH1 (NP_000152) VersaClone cDNA

Name: Human GCH1 (NP_000152) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2883
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC2883

Submit a review

Product Documents

100% Guarantee

Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_000152

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GCH1

GCH1 encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.

Long Name

GTP Cyclohydrolase 1

Alternate Names

DYT5, DYT5a, GTP-CH-1, GTP-CH-I, GTPCH1

Entrez Gene IDs

2643 (Human)

Gene Symbol

GCH1

UniProt

NP_000152

Additional GCH1 Products

Product Documents for Human GCH1 (NP_000152) VersaClone cDNA

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human GCH1 (NP_000152) VersaClone cDNA

For research use only

Customer Reviews for Human GCH1 (NP_000152) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human GCH1 (NP_000152) VersaClone cDNA and earn rewards!

Have you used Human GCH1 (NP_000152) VersaClone cDNA?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image