Human IGDCC3 Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB8559R-100UG
Detection of IGDCC3 in HEK293 Human Cell Line Transfected with Human IGDCC3 and eGFP by Flow Cytometry.
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Human IGDCC3 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human IGDCC3 in direct ELISAs.
Source
Monoclonal Mouse IgG1 Clone # 920038
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Human embryonic kidney cell line HEK293-derived recombinant human IGDCC3
Leu36-Gly640
Accession # Q8IVU1
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of IGDCC3 antibody in HEK293 Human Cell Line Transfected with Human IGDCC3 and eGFP antibody by Flow Cytometry. View Larger

Detection of IGDCC3 in HEK293 Human Cell Line Transfected with Human IGDCC3 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human IGDCC3 and eGFP was stained with either (A) Mouse Anti-Human IGDCC3 Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB8559R) or (B) Mouse IgG1Alexa Fluor 647 Isotype Control (Catalog # IC002R). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: IGDCC3

IGDCC3 (Immunoglobulin superfamily DCC subclass member 3), also known as Punc, is 814 aa single-pass type I transmembrane protein that shares 91% aa sequence identity with mouse IGDCC3 in the extracellular domain.  It is a member of the neural cell adhesion molecule family and contains two fibronectin type III repeats and four immunoglobulin-like domains.  IDGCC3 is high expressed in the brain, and has been suggested to play a role in motor coordination.  It has also been suggested to play a role in breast cancer. 

Long Name
Immunoglobulin Superfamily, DCC Subclass, Member 3
Entrez Gene IDs
9543 (Human); 19289 (Mouse)
Alternate Names
HsT18880; IGDCC3; immunoglobulin superfamily DCC subclass member 3; immunoglobulin superfamily, DCC subclass, member 3; PUNC; Putative neuronal cell adhesion moleculePUNCHsT18880

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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