Human IGDCC3 Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB8559R-025
Detection of IGDCC3 in HEK293 Human Cell Line Transfected with Human IGDCC3 and eGFP by Flow Cytometry.
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Human IGDCC3 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human IGDCC3 in direct ELISAs.
Source
Monoclonal Mouse IgG1 Clone # 920038
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Human embryonic kidney cell line HEK293-derived recombinant human IGDCC3
Leu36-Gly640
Accession # Q8IVU1
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 647

Applications

Recommended Concentration
Sample
Flow Cytometry
5 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of IGDCC3 in HEK293 Human Cell Line Transfected with Human IGDCC3 and eGFP by Flow Cytometry. View Larger

Detection of IGDCC3 in HEK293 Human Cell Line Transfected with Human IGDCC3 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human IGDCC3 and eGFP was stained with either (A) Mouse Anti-Human IGDCC3 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB8559R) or (B) Mouse IgG1 Alexa Fluor 647 Isotype Control (Catalog # IC002R). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: IGDCC3

IGDCC3 (Immunoglobulin superfamily DCC subclass member 3), also known as Punc, is 814 aa single-pass type I transmembrane protein that shares 91% aa sequence identity with mouse IGDCC3 in the extracellular domain.  It is a member of the neural cell adhesion molecule family and contains two fibronectin type III repeats and four immunoglobulin-like domains.  IDGCC3 is high expressed in the brain, and has been suggested to play a role in motor coordination.  It has also been suggested to play a role in breast cancer. 

Long Name
Immunoglobulin Superfamily, DCC Subclass, Member 3
Entrez Gene IDs
9543 (Human); 19289 (Mouse)
Alternate Names
HsT18880; IGDCC3; immunoglobulin superfamily DCC subclass member 3; immunoglobulin superfamily, DCC subclass, member 3; PUNC; Putative neuronal cell adhesion moleculePUNCHsT18880

Product Datasheets

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