Indian Hedgehog (Ihh), Sonic Hedgehog (Shh), and Desert Hedgehog (Dhh) are important signaling molecules during embryonic development and are highly conserved within and across species. Mouse Ihh cDNA encodes a 411 amino acid (aa) polypeptide with a predicted 27 aa signal peptide. Post-translational processing yields a 19 kDa lipid-modified N-terminal domain that is the signaling molecule. At the cell surface, Ihh activity is mediated by binding the 12-pass transmembrane receptor, Patched (Ptc), and signaling through the 7-pass transmembrane G-protein coupled receptor, Smoothened (Smo).
Human Indian Hedgehog/Ihh (NP_002172.2) VersaClone cDNA
R&D Systems | Catalog # RDC3360
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Indian Hedgehog/Ihh
Alternate Names
BDA1, HHG2, Ihh
Gene Symbol
IHH
UniProt
Additional Indian Hedgehog/Ihh Products
Product Documents for Human Indian Hedgehog/Ihh (NP_002172.2) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Indian Hedgehog/Ihh (NP_002172.2) VersaClone cDNA
For research use only
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