Leukocyte Immunoglobulin-like Receptor 6 (LIR-6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged aa within the TM domain which interacts with FcRgamma. Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR-6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity.
Human LILRA1/CD85i/LIR-6 (NP_006854) VersaClone cDNA
R&D Systems | Catalog # RDC1276
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: LILRA1/CD85i/LIR-6
Long Name
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 1
Alternate Names
CD85i, LIR-6, LIR6
Entrez Gene IDs
11024 (Human)
Gene Symbol
LILRA1
UniProt
Additional LILRA1/CD85i/LIR-6 Products
Product Documents for Human LILRA1/CD85i/LIR-6 (NP_006854) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human LILRA1/CD85i/LIR-6 (NP_006854) VersaClone cDNA
For research use only
Related Research Areas
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