Home / Nbs1 / Human/Mouse/Rat Nbs1 Alexa Fluor® 532-conjugated Antibody

Human/Mouse/Rat Nbs1 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB1573X Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB1573X-100UG

Save 15% on Select RUO Reagents. See Details. 

Product Details
FAQs
Reviews
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse/Rat Nbs1 Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human, mouse, and rat Nbs1 in Western blots.
Source
Monoclonal Mouse IgG2b Clone # 206919
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human Nbs1
Pro498-Arg754
Accession # O60934
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Knockout Validated
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Nbs1

The Nijmegen Breakage Syndrome 1 (Nbs1) protein is a member of the Mre11/Rad50/Nbs1 (MRN) protein complex that binds to DNA double-strand breaks in cells exposed to DNA damaging agents. In addition, the MRN complex colocalizes with replication forks during DNA replication. The MRN complex plays an important role in routine cell cycle progression and genotoxic stress responses by facilitating DNA repair. In fact, mutation of the nbs1 gene and resultant loss of Nbs1 protein expression in humans results in the chromosomal instability disease, Nijmegen Breakage Syndrome.

Long Name
Nijmegen Breakage Syndrome 1
Entrez Gene IDs
4683 (Human); 27354 (Mouse); 85482 (Rat)
Alternate Names
ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; MGC87362; NBN; NBS; Nbs1; NBS1P95; Nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; p95 protein of the MRE11/RAD50 complex; p95

Product Datasheets

You must select a language.

x
Product Datasheet
COA

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Human/Mouse/Rat Nbs1 Alexa Fluor® 532-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human/Mouse/Rat Nbs1 Alexa Fluor® 532-conjugated Antibody and earn rewards!

Have you used Human/Mouse/Rat Nbs1 Alexa Fluor® 532-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review