Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0497
Product Details
Citations (1)
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Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA Summary

SLC11A1 (NRAMP1) is a member of the solute carrier family of multi-pass membrane proteins. It functions as a proton-coupled divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in SLC11A1 have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. Alternatively spliced variants that encode different protein isoforms have been described.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: NRAMP1/SLC11A1

Long Name
Natural Resistance-associated Macrophage Protein 1
Entrez Gene IDs
6556 (Human); 18173 (Mouse); 316519 (Rat)
Alternate Names
natural resistance-associated macrophage protein 1; LSH; member 1; NRAMP 1; NRAMP1; NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1; NRAMPnatural resistance-associated macrophage protein 1; SLC11A1; solute carrier family 11 (proton-coupled divalent metal ion transporters)

Citation for Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. c-Src kinase is involved in the tyrosine phosphorylation and activity of SLC11A1 in differentiating macrophages
    Authors: YZ Xu, T Thuraising, C Kanagarath, S Tao, D Radzioch
    PLoS ONE, 2018;13(5):e0196230.  2018

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