SLC11A1 (NRAMP1) is a member of the solute carrier family of multi-pass membrane proteins. It functions as a proton-coupled divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in SLC11A1 have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. Alternatively spliced variants that encode different protein isoforms have been described.
Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA
R&D Systems | Catalog # RDC0497
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: NRAMP1/SLC11A1
Long Name
Natural Resistance-associated Macrophage Protein 1
Alternate Names
LSH, SLC11A1
Gene Symbol
SLC11A1
UniProt
Additional NRAMP1/SLC11A1 Products
Product Documents for Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA
For research use only
Citations for Human NRAMP1/SLC11A1 (NP_000569) VersaClone cDNA
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