Human PTP rho/PTPRT Alexa Fluor™ Plus 488‑conjugated Antibody

R&D Systems | Catalog # AF3697AFP488

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG
View all PTP rho/PTPRT Primary Antibodies »

Product Specifications

Specificity

Detects human PTPρ/PTPRT in Western blots. In Western blots, no cross-reactivity with recombinant human LAR, PTPRM, K, S, G or DEP1/CD148 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human PTP rho/PTPRT Alexa Fluor™ Plus 488‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PTP rho/PTPRT

Protein Tyrosine Phosphatase, Receptor-type T (PTPRT), also known as RPTPrho, dephosphorylates tyrosine residues in proteins. PTPRT is present in many tissues, including brain, heart, lung, and colon. Genetic screening of colon cancers indicates that the PTPRT gene has a high incidence of missense mutations that reduce phosphatase activity in the encoded protein. Overexpression of intact PTPRT in cancer cell lines inhibits cell proliferation, suggesting that the phosphatase is a tumor suppressor.

Long Name

Protein Tyrosine Phosphatase Receptor-type T

Alternate Names

PTPRT, RPTP-rho

Entrez Gene IDs

11122 (Human); 19281 (Mouse); 362263 (Rat)

Gene Symbol

PTPRT

UniProt

O14522

Additional PTP rho/PTPRT Products

Product Documents for Human PTP rho/PTPRT Alexa Fluor™ Plus 488‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human PTP rho/PTPRT Alexa Fluor™ Plus 488‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

Epigenetics
Phosphatases and Regulators

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