Human RNF43 (NP_060233) VersaClone cDNA

Catalog # Availability Size / Price Qty
R&D Systems VersaClone cDNA Plasmids
1 Image
Product Details

Human RNF43 (NP_060233) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Product Datasheets

You must select a language.


Background: RNF43

RNF43 (RING finger protein 43) is an E3 ubiquitin ligase that may be expressed on the plasma membrane or intracellularly. It can associate with the nuclear matrix protein HAP95/AKAP8L, the ubiquitin ligase NEDL1, and p53. It also interacts with the cell surface ubiquitin ligase ZNRF3, and both RNF43 and ZNRF3 antagonize Wnt signaling by promoting the turnover of Frizzled receptors. Interaction with the R-Spondin Wnt-regulating proteins can also antagonize ZNRF3. RNF43 is frequently overexpressed in cancers, correlating with growth-promoting activity and colorectal and hepatocellular cancer pathogenesis. It is expressed in intestinal epithelial stem cells in colon crypts, where it limits the ability of Wnts to induce proliferation.

Long Name
Ring Finger Protein 43
Entrez Gene IDs
54894 (Human); 207742 (Mouse); 303412 (Rat)
Alternate Names
DKFZp781H02126; DKFZp781H0392; FLJ20315; FLJ77466; FLJ99338; MGC125630; ring finger protein 43; RNF124; RNF43; URCC


No product specific FAQs exist for this product, however you may

View all cDNA Clone FAQs

Reviews for Human RNF43 (NP_060233) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human RNF43 (NP_060233) VersaClone cDNA and earn rewards!

Have you used Human RNF43 (NP_060233) VersaClone cDNA?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review