Human SorCS2 (NP_065828.2) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC3175
Human SorCS2 (NP_065828.2) VersaClone cDNA
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Human SorCS2 (NP_065828.2) VersaClone cDNA Summary

Specifications

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: SorCS2

SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.

Long Name
Sortilin-related VPS10 Domain Containing Receptor 2
Entrez Gene IDs
57537 (Human); 81840 (Mouse)
Alternate Names
KIAA1329VPS10 domain receptor protein; SorCS2; sortilin-related VPS10 domain containing receptor 2; VPS10 domain-containing receptor SorCS2

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