Human SorCS3 (NP_055793.1) VersaClone cDNA

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Human SorCS3 (NP_055793.1) VersaClone cDNA
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Human SorCS3 (NP_055793.1) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: SorCS3

SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.

Long Name
Sortilin-related VPS10 Domain Containing Receptor 3
Entrez Gene IDs
22986 (Human); 66673 (Mouse); 294043 (Rat)
Alternate Names
6330404A12Rik; KIAA1059SORCS; SorCS3; sortilin-related VPS10 domain containing receptor 3; VPS10 domain receptor protein SORCS 3 (SORCS3); VPS10 domain-containing receptor SorCS3


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