Human USP24 (NP_056121) VersaClone cDNA

R&D Systems | Catalog # RDC1855

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: USP24

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Long Name

Ubiquitin Specific Protease 24

Alternate Names

Deubiquitinating enzyme 24, EC 3.4.19.12, FLJ31309, KIAA1057ubiquitin carboxyl-terminal hydrolase 24, ubiquitin specific peptidase 24, ubiquitin specific protease 24, ubiquitin thioesterase 24, Ubiquitin thiolesterase 24, ubiquitin-specific processing protease 24, Ubiquitin-specific-processing protease 24

Entrez Gene IDs

23358 (Human); 329908 (Mouse); 313427 (Rat)

Gene Symbol

USP24

UniProt

Additional USP24 Products

Product Documents for Human USP24 (NP_056121) VersaClone cDNA

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human USP24 (NP_056121) VersaClone cDNA

For research use only

Related Research Areas

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