Human VAChT/SLC18A3 (AAA20497) VersaClone cDNA

R&D Systems | Catalog # RDC0901

R&D Systems
100% Guarantee

Key Product Details

Species

Human

Accession Number

AAA20497

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: VAChT/SLC18A3

Vesicular Acetylcholine Transporter (VAChT), (approx. 70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate. VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer's disease and other nervous system disorders.

Long Name

Vesicular Acetylcholine Transporter/Solute Carrier Family 18 Member 3

Alternate Names

SLC18A3

Entrez Gene IDs

6572 (Human); 20508 (Mouse); 60422 (Rat)

Gene Symbol

SLC18A3

UniProt

AAA20497

Additional VAChT/SLC18A3 Products

Product Documents for Human VAChT/SLC18A3 (AAA20497) VersaClone cDNA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human VAChT/SLC18A3 (AAA20497) VersaClone cDNA

For research use only

Customer Reviews for Human VAChT/SLC18A3 (AAA20497) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human VAChT/SLC18A3 (AAA20497) VersaClone cDNA and earn rewards!

Have you used Human VAChT/SLC18A3 (AAA20497) VersaClone cDNA?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for cDNA Clones