The cell-surface transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) and its homologue ring finger 43 (RNF43) are negative feedback regulators of Wnt signaling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signaling by promoting the turnover of frizzled and LRP6. R-spondin may enhance Wnt signaling by inhibiting ZNRF3. ZNRF3 may be a target for therapeutic exploration.
Human ZNRF3 (NP_001193927) VersaClone cDNA
R&D Systems | Catalog # RDC0508
Loading...
Loading...
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: ZNRF3
Long Name
Zinc and Ring Finger 3
Alternate Names
BK747E2.3, KIAA1133, RNF203
Gene Symbol
ZNRF3
UniProt
Additional ZNRF3 Products
Product Documents for Human ZNRF3 (NP_001193927) VersaClone cDNA
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human ZNRF3 (NP_001193927) VersaClone cDNA
For research use only
Related Research Areas
Customer Reviews for Human ZNRF3 (NP_001193927) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human ZNRF3 (NP_001193927) VersaClone cDNA and earn rewards!
Have you used Human ZNRF3 (NP_001193927) VersaClone cDNA?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...