IEM 1925 dihydrobromide

   
Product Datasheet
Catalog Number:4198
Chemical Name:N-(1-Phenylcyclohexyl)-1,5-pentanediamine dihydrobromide
Product Details
Reviews
Biological Activity
Voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluR2 subunit-lacking receptors more potently than GluR2-containing receptors (KD for GluR2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 (Cat. No. 1636) and IEM 1754 (Cat. No. 4199) due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.
Technical Data
  • M.Wt:
    422.24
  • Formula:
    C17H28N2.2HBr
  • Solubility:
    Soluble to 100 mM in water and to 50 mM in DMSO
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    258282-23-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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