Recombinant Human IL-18 BPa/IL18BP His Protein

Name: Recombinant Human IL-18 BPa/IL18BP His Protein
Brand: Novus Biologicals
SKU: NBP2-23150
Price: 349 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-23150

Submit a review

Product Documents

100% Guarantee

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all IL-18 BPa Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 31-194 of Human IL-18 BPa/IL18BP

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human IL-18 BPa/IL18BP His Protein

SDS-PAGE: Recombinant Human IL-18 BPa/IL18BP His Protein [NBP2-23150]

SDS-Page: Recombinant Human IL-18 BPa/IL18BP Protein [NBP2-23150]

Formulation, Preparation, and Storage

NBP2-23150

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-18 BPa

IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.

Long Name

Interleukin 18 Binding Protein Isoform a

Alternate Names

IL18 BPa, IL18BP

Gene Symbol

IL18BP

Additional IL-18 BPa Products

Product Documents for Recombinant Human IL-18 BPa/IL18BP His Protein

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Recombinant Human IL-18 BPa/IL18BP His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

IL-1 Family

Customer Reviews for Recombinant Human IL-18 BPa/IL18BP His Protein

There are currently no reviews for this product. Be the first to review Recombinant Human IL-18 BPa/IL18BP His Protein and earn rewards!

Have you used Recombinant Human IL-18 BPa/IL18BP His Protein?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image