Key Product Details

Species Reactivity

Human

Applications

Western Blot, ICC/IF (Negative)

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Rabbit IgG
View all ILVBL Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an internal portion of the human ILVBL protein (between residues 350-500) [UniProt A1L0T0]

Localization

Membrane; Single-pass membrane protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for ILVBL Antibody [DyLight 405]

Application
Recommended Usage

ICC/IF (Negative)

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ILVBL

ILVBL (IHAS) is a ubiquitiously expressed 68 kDa membrane protein which belongs to a family of thiamine pyrophosate-binding proteins. While ILVB is known to be involved in the initial steps of branched chain amino acid synthesis, the exact role of this protein in mammals is not known. However, the gene does show similarity to the acetolactate synthase enzyme found in bacteria. Recently investigators mapped the ILVBL gene to the 19p13.1 chromosome. This region coincides with the CADASIL critical region, which is an autosomal dominant condition that results in infarcts of the subcortical regions of the brain leading to dementia. However, there were no mutations in this gene of CADISIL patients, so its role, if any, is not known (PMID:8954801).

Alternate Names

acetolactate synthase homolog, acetolactate synthase-like protein, AHASFLJ39061,209L8, EC 2.2.1, EC 2.2.1.-, ILV2H, ilvB (bacterial acetolactate synthase)-like, IlvB-like protein, MGC1269, MGC19535

Gene Symbol

ILVBL

Additional ILVBL Products

Product Documents for ILVBL Antibody [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for ILVBL Antibody [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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