Integrin alpha L/CD11a Antibody (I21/7) [FITC]

Name: Integrin alpha L/CD11a Antibody (I21/7) [FITC]
Brand: Novus Biologicals
SKU: NBP1-27871
Price: 499 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-27871

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Mouse

Applications

Block/Neutralize

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # I21/7

View all Integrin alpha L/CD11a Primary Antibodies »

Product Specifications

Immunogen

Whole BW5147 cells

Specificity

Mouse/Human CD11a

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for Integrin alpha L/CD11a Antibody (I21/7) [FITC]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [FITC] [NBP1-27871] -

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [FITC] [NBP1-27871] - BALB/c mouse splenocytes were stained Rat Anti-Mouse NBP1-27871

Applications for Integrin alpha L/CD11a Antibody (I21/7) [FITC]

Application

Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Integrin alpha L/CD11a

The monoclonal antibody I21/7 reacts with the alpha subunit of mouse CD11a, also known as Leukocyte Function-associated Antigen-1 (LFA-1) and a member of the integrin family of cell adhesion molecules. (1, 2) The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. (2) CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1. (1, 2)

Alternate Names

CD11a, ITGAL, LFA-1 alpha, Ly-15, Ly-21

Gene Symbol

ITGAL

Additional Integrin alpha L/CD11a Products

Product Documents for Integrin alpha L/CD11a Antibody (I21/7) [FITC]

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Certificate of Analysis

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Product Specific Notices for Integrin alpha L/CD11a Antibody (I21/7) [FITC]

Protect conjugated forms from light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.